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  1. Depression (major depressive disorder) - Symptoms and causes

    Oct 14, 2022 · Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think …

  2. Major depressive disorder - Wikipedia

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [10] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or …

  3. Major Depression - Johns Hopkins Medicine

    Depression is a serious mood disorder. It touches every part of your life and is caused by a chemical imbalance in your brain. Treatment involves medicine and counseling.

  4. Major Depression (Clinical Depression) Symptoms, Treatments, and …

    Sep 27, 2024 · WebMD gives an overview of clinical -- or major -- depression, including its causes, symptoms, and treatment.

  5. Major Depressive Disorder: Symptoms, Causes, Treatment

    Dec 11, 2025 · Major depressive disorder, also known as depression, is a mood disorder that interferes with daily life. Learn about symptoms, causes, and treatment.

  6. Depression - National Institute of Mental Health (NIMH)

    Depression (also called major depressive disorder or clinical depression) is different. It can cause severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or …

  7. Major Depressive Disorder | Johns Hopkins Psychiatry Guide

    Major Depressive Disorder answers are found in the Johns Hopkins Psychiatry Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web.

  8. Major depression: MedlinePlus Medical Encyclopedia

    Apr 19, 2025 · Depression is feeling sad, blue, unhappy, or down in the dumps. Most people feel this way once in a while. Major depression is a mood disorder. It occurs when feelings of sadness, loss, …

  9. Major Depressive Disorder | National Alliance on Mental Illness

    When more severe symptoms like lack of energy and hopelessness develop in multiple areas of a person’s life along with persistent sadness over at least two weeks, they may be experiencing a …

  10. Major Depressive Disorder - MentalHealth.com

    Aug 7, 2025 · Discover how major depressive disorder negatively affects well-being, physical and mental health, and how treatment and support offer hope.