A final discussion point is real-world applicability. Although PHAROS presents exceptional PFS, the modest difference between PFS and OS suggests that resistance remains a major hurdle. As with other ...

DECLARATION is a Phase 3, randomized, placebo-controlled clinical trial to evaluate the safety and efficacy of VYD2311 in the prevention of COVID ...

Objective To determine whether a full-scale randomised control trial (RCT) assessing the efficacy and cost-effectiveness of a housing led Critical Time Intervention (CTI) is feasible and acceptable.

Objective To investigate the effectiveness of cryotherapy on pain intensity, range of motion (ROM), swelling and function in the postoperative care of musculoskeletal disorders. Design Systematic ...

A new analysis of clinical trial data indicates that psilocybin-assisted psychotherapy provides immediate relief for anxiety ...

A systematic review and meta-analysis finds that weight-loss interventions are associated with decreased psoriasis severity ...

Introduction Nasogastric tubes (NGTs) are standard practice in the management of adhesive small bowel obstruction (ASBO). Their insertion can be associated with significant patient discomfort and ...

Background The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains controversial, with conflicting evidence from landmark trials. We aimed to assess the ...

EMA provided overall agreement with the proposed Phase 3 clinical trial of VCN-01 in combination with ...

GLP-1 drugs show a potential link to reduced epilepsy risk in people with type 2 diabetes. People taking GLP-1 drugs were 16% less likely to develop epilepsy than those on DPP-4 inhibitors.

A systematic review of trials including more than 2,300 adults with chronic pain found that cannabis-based products with ...